COSG is an accurate and efficient marker gene identification method for single cell sequencing data.
COSG is applicable to single-cell RNA sequencing data, single-cell ATAC sequencing data and spatially resolved transcriptome data.
COSG is fast and scalable for ultra-large datasets of million-scale cells (less than two minutes for one million cells with one CPU core).
Marker genes or genomic regions identified by COSG are more indicative and with greater cell-type specificity.
Min Dai (2021-06-15)